QUESTION 1 You have a hybrid Exchange Server 2016 organization. Some of the mailboxes in the research department are hosted on-premises. Other mailboxes in the research department are stored in Microsoft Office 365. You need to search the mailboxes in the research department for email messages that contain a specific keyword in the message body. What should you do? A. From the Exchange Online Exchange admin center, search the delivery reports. B. Form the on-premises Exchange center, search the delivery reports. C. From the Exchange Online Exchange admin SY0-401 exam center, create a new In-Place eDiscovery & Hold. D. From the Office 365 Compliance Center, create a new Compliance Search. E. From the on-premises Exchange admin center, create a new In-Place eDiscovery & Hold. Correct Answer: E QUESTION 2 You have an Exchange Server 2016 organization. You plan to enable Federated Sharing. You need to create a DNS record to store the Application Identifier (AppID) of the domain for the federated trust. Which type of record should you create? A. A B. CNAME C. SRV D. TXT Correct Answer: D QUESTION 3 Your company has an Exchange Server 2016 200-310 exam Organization. The organization has a four- node database availability group (DAG) that spans two data centers. Each data center is configured as a separate Active Directory site. The data centers connect to each other by using a high-speed WAN link. Each data center connects directly to the Internet and has a scoped Send connector configured. The company's public DNS zone contains one MX record. You need to ensure that if an Internet link becomes unavailable in one data center, email messages destined to external recipients can 400-101 exam be routed through the other data center. What should you do? A. Create an MX record in the internal DNS zone B. B. Clear the Scoped Send Connector check box C. Create a Receive connector in each data center. D. Clear the Proxy through Client Access server check box Correct Answer: AQUESTION 4 Your network contains a single Active Directory forest. The forest contains two sites named Site1 and Site2. You have an Exchange Server 2016 organization. The organization contains two servers in each site. You have a database availability group (DAG) that spans both sites. The file share witness is in Site1. If a power failure occurs at Site1, you plan to mount the databases in Site2. When the power is restored in Site1, you Cisco CCNP Security 300-207 exam SITCS need to prevent the databases from mounting in Site1. What should you do? A. Disable AutoReseed for the DAG. B. Implement an alternate file share witness. C. Configure Datacenter Activation Coordination (DAC) mode. D. Force a rediscovery of the EX200 exam network when the power is restored. Correct Answer: C QUESTION 5 A new company has the following: Two offices that connect to each other by using a low-latency WAN link In each office, a data center that is configured as a separate subnet Five hundred users in each office You plan to deploy Exchange Server 2016 to the network. You need to recommend which Active Directory deployment to use to support the Exchange Server 2016 deployment What is the best recommendation to achieve the goal? A. Deploy two forests that each contains one site and one site link. Deploy two domain controllers to each forest. In each forest configure one domain controller as a global catalog server B. Deploy one forest that contains one site and one site link. Deploy four domain controllers. Configure all of the domain controllers as global catalog servers. C. Deploy one forest that contains two sites and two site links. Deploy two domain controllers to each site in each site, configure one domain controller as a global catalog server D. Deploy one forest that contains two sites and one site link. Deploy two domain controllers to each site. Configure both domain controllers as global catalog servers Correct Answer: C QUESTION 6 How is the IBM Content Template Catalog delivered for installation? A. as an EXE file B. as a ZIP file of XML files C. as a Web Appli cati on Archive file D. as a Portal Application Archive file Correct Answer: D QUESTION 7 Your company has a data center. The data center contains a server that has Exchange Server 2016 and the Mailbox server role installed. Outlook 300-101 exam anywhere clients connect to the Mailbox server by using thename outlook.contoso.com. The company plans to open a second data center and to provision a database availability group (DAG) that spans both data centers. You need to ensure that Outlook Anywhere clients can connect if one of the data centers becomes unavailable. What should you add to DNS? A. one A record B. two TXT records C. two SRV records D. one MX record Correct Answer: A QUESTION 8 You have an Exchange Server 2016 EX300 exam organization. The organization contains a database availability group (DAG). You need to identify the number of transaction logs that are in replay queue. Which cmdlet should you use? A. Test-ServiceHealth B. Test-ReplicationHealth C. Get-DatabaseAvailabilityGroup D. Get-MailboxDatabaseCopyStatus Correct Answer: D QUESTION 9 All users access their email by using Microsoft Outlook 2013 From Performance Monitor, you discover that the MSExchange Database\I/O Database Reads Average Latency counter displays values that are higher than normal You need to identify the impact of the high counter values on user connections in the Exchange Server organization. What are two client connections 400-051 exam that will meet performance? A. Outlook on the web B. IMAP4 clients C. mobile devices using Exchange ActiveSync D. Outlook in Cached Exchange ModeE. Outlook in Online Mode Correct Answer: CE QUESTION 10 You work for a company named Litware, Inc. that hosts all email in Exchange Online. A user named User1 sends an email message to an Pass CISCO 300-115 exam - test questions external user User 1 discovers that the email message is delayed for two hours before being delivered. The external user sends you the message header of the delayed message You need to identify which host in the message path is responsible for the delivery delay. What should you do? A. Review the contents of the protocol logs. B. Search the message tracking logs. C. Search the delivery reports 200-355 exam for the message D. Review the contents of the application log E. Input the message header to the Exchange Remote Connectivity Analyzer Correct Answer: E QUESTION 11 You have an Exchange Server 2016 organization. The organization contains three Mailbox servers. The servers are configured as shown in the following table You have distribution group named Group1. Group1 contains three members. The members are configured as shown in the following table. You discover that when User1 sends email messages to Group1, all of the messages are delivered to EX02 first. You need to identify why the email messages sent to Group1 are sent to EX02 instead. What should you identify? A. EX02 is configured as an expansion server. B. The arbitration mailbox is hosted 300-320 exam on EX02.C. Site2 has universal group membership caching enabled. D. Site2 is configured as a hub site. Correct Answer: A

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Miosite

Definição

A miosite é uma condição rara que afeta os músculos. O termo miosite significa “inflamação dos músculos”.

Os principais sinais são fraqueza muscular, músculos doloridos ou doloridos, tropeços ou quedas e cansaço extremo após andar ou ficar de pé. Se tiver algum destes sintomas, deverá ir ver o seu médico.

A miosite geralmente é causada por um problema subjacente com o sistema imunológico, onde, por engano, ataca o tecido saudável.

A Miosite

A Miosite significa inflamação dos músculos que você usa para mover seu corpo. Uma lesão, infecção ou doença auto-imune pode causar isso.

Dois tipos específicos são: polimiosite e dermatomiosite.

A polimiosite causa fraqueza muscular, geralmente nos músculos mais próximos do tronco do seu corpo.

Dermatomiosite causa fraqueza muscular, além de uma erupção cutânea.

Outros sintomas de miosite podem incluir:

Fadiga após andar ou ficar de pé
Tropeçar ou cair
Dificuldade para engolir ou respirar

Os médicos podem usar um exame físico, exames laboratoriais, exames de imagem e uma biópsia muscular para diagnosticar a miosite. Não há cura para essas doenças, mas você pode tratar os sintomas. A polimiosite e a dermatomiosite são primeiramente tratadas com altas doses de um corticosteróide. Outras opções incluem medicamentos, fisioterapia, exercícios, terapia de calor, dispositivos auxiliares e descanso.

Tipos de miosite

Miosite
Miosite

Existem diferentes tipos de miosite que afetam os músculos, incluindo:

Polimiosite – que afeta muitos músculos diferentes, particularmente os ombros, quadris e músculos da coxa; é mais comum em mulheres e tende a afetar pessoas de 30 a 60 anos

Dermatomiosite – que, além de afetar os músculos, provoca erupções cutâneas; também é mais comum em mulheres e afeta adultos e crianças
miosite reativa pós-infecciosa – que você pode obter após algumas infecções virais e faz com que os músculos fiquem inflamados; este tipo de miosite é geralmente leve e se instala sem tratamento

Miosite do corpo de inclusão (IBM) – que causa fraqueza muscular no quadríceps (músculos principais da coxa), fraqueza nos músculos do antebraço que flexionam os dedos e fraqueza nos músculos abaixo do joelho, o que pode causar queda do pé, dificultando o levantamento a parte da frente do seu pé e dos pés e fazendo com que o pé se arraste no chão ao caminhar. A Miosite do corpo de inclusão (IBM) é mais comum em homens e tende a ocorrer após os 50 anos de idade

Causas da Miosite

A miosite pode ser provocada por uma lesão, infecção ou doenças auto-imunes, tais como artrite reumatóide e lúpus. Os vírus, incluindo o resfriado comum, a gripe e o vírus da imunodeficiência humana (HIV), também estão associados à miosite. Certos medicamentos (como as estatinas) e drogas ilegais (como a cocaína) também podem causar miosite.

Tratamento de miosite

Não há cura para miosite, mas os sintomas podem ser gerenciados. Normalmente, o tratamento começa com altas doses de corticosteróides para reduzir rapidamente a inflamação. No entanto, miosite varia de pessoa para pessoa, por isso é importante tratar a causa subjacente da doença, seja antibióticos para infecções ou drogas anti-reumáticas modificadoras da doença (DMARDs – drogas Modificadoras de Atividade da Doença) para doença auto-imune.

Drogas imunossupressoras modificadoras da doença, como azatioprina e metotrexato, podem ser usadas quando os corticosteroides não funcionam. A imunoglobulina intravenosa também pode ser usada.

O que é Miosite Viral?

A miosite viral é uma complicação rara de uma infecção viral que causa inflamação, enfraquecimento e dor nos músculos esqueléticos.

Uma pessoa pode ter dor muito isolada em um único grupo muscular, como músculos ao redor do quadril ou do ombro, ou a condição pode causar desconforto em muitos lugares diferentes do corpo de uma só vez.

Os sintomas tendem a se desenvolver rapidamente, e um indivíduo pode se ver incapaz de sair da cama nos últimos estágios da miosite viral.

O tratamento consiste tipicamente em um curso de drogas antivirais, fluidos para prevenir a desidratação, esteróides para reduzir a inflamação e um longo período de repouso no leito.

Infecção muscular e inflamação não são comuns com a maioria das infecções virais.

A maioria dos casos de miosite está relacionada a condições autoimunes em que o sistema imunológico ataca fibras nervosas e musculares saudáveis por engano, agindo como se fossem patógenos perigosos.

No caso da miosite viral, no entanto, o ataque do sistema imunológico não é equivocado. Patógenos virais realmente representam uma ameaça para o corpo.

O vírus da imunodeficiência humana (HIV) é a causa mais comum de miosite. Infecções agudas de coxsackievirus, influenza e vários outros patógenos também podem levar à inflamação muscular.

Uma pessoa que desenvolve miosite provavelmente sentirá dor, fraqueza e inchaço em um ou mais músculos. O quadríceps nas pernas e músculos da parte inferior das costas são os locais mais comuns. A inflamação também pode afetar os ombros, braços e pescoço. A miosite pode ser acompanhada por sintomas mais gerais de febre, fadiga e dores no corpo inteiro.

Em casos graves, os pulmões, os rins ou o coração também podem ser afetados, levando a complicações potencialmente fatais.

Um médico pode diagnosticar a miosite viral com um exame físico e exames de sangue. O médico fará perguntas sobre a história e os sintomas do paciente e examinará diferentes músculos para localizar locais sensíveis. Testes de imagem, como ultra-sonografias e raios X, ajudam a confirmar o inchaço e a inflamação nos músculos. Amostras de sangue são rastreadas para a presença do HIV ou outro vírus que pode ser responsável pelos sintomas.

O tratamento da miosite depende em grande parte do tipo de vírus envolvido e da gravidade dos sintomas.

Pacientes com dor menor e febre baixa são prescritos medicamentos antivirais e instruídos a descansar bastante até que os sintomas desapareçam. Se uma pessoa tem desconforto significativo, ela pode ser hospitalizada para que antivirais, fluidos e corticosteróides possam ser administrados por via intravenosa.

Indivíduos com HIV-positivos tipicamente requerem tratamento inicial mais agressivo e terapia médica contínua ao longo da vida para suas condições. A maioria dos casos de miosite viral pode ser resolvida ou pelo menos melhorada com tratamento cuidadoso.

Fonte: www.ninds.nih.gov/www.wisegeek.org/www.nhs.uk/www.arthritis.org

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